Immune Responses to HSP65/60 in Periodontal Disease

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Immune Responses to HSP65/60 in Periodontal Disease

Chronic periodontitis (CP) is a chronic inflammatory condition which destroys the supporting tissues of teeth and increases in prevalence with age. Immune responses against heat shock proteins (HSP) can be cross-reactive among bacterial and human antigens. There is evidence that microbial HSP65 and human HSP60 are involved in periodontal disease. The aim of this study is to investigate immune r...

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Humoral immune responses to periodontal pathogens in the elderly

PURPOSE Elderly people are thought to be more susceptible to periodontal disease due to reduced immune function associated with aging. However, little information is available on the nature of immune responses against putative periodontal pathogens in geriatric patients. The purpose of this study was to evaluate the serum IgG antibody responses to six periodontal pathogens in geriatric subjects...

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Periodontal diseases are characterized by localized infections and inflammatory conditions that directly affect teeth supporting structures which are the major cause of tooth loss. Several studies have demonstrated the involvement of autoimmune responses in periodontal disease. Evidences of involvement of immunopathology have been reported in periodontal disease. Bacteria in the dental plaque i...

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The Impact of Bacteria-Induced Adaptive Immune Responses in Periodontal Disease

More than one microorganism causes periodontal disease, like many infectious diseases in humans. Because of the complexity of “polymicrobial infections”, their study requires a multidisciplinary approach, employing specific in vitro techniques, and various animal models (Bakaletz 2004). Inherently, no one approach or animal model can completely elucidate the mechanisms of periodontal disease. N...

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Immune responses to pertussis vaccines and disease.

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ژورنال

عنوان ژورنال: Journal of Immune Based Therapies, Vaccines and Antimicrobials

سال: 2012

ISSN: 2168-1546,2168-1554

DOI: 10.4236/jibtva.2012.12002